The FogBugz database is down or could not be found.

Error: -2146232060: Timeout expired. The timeout period elapsed prior to completion of the operation or the server is not responding.

For security reasons, this cannot be fixed over the web.

Please edit the registry on the FogBugz server. The setting you want is HKEY_LOCAL_MACHINE\SOFTWARE\Fog Creek Software\FogBugz\C:/FogBugz/website\sConnectionString.
Common connection strings can be found at connectionstrings.com. (Also please note that if your SQL machine is on a different server than your web server, you may have to use SQL Server Authentication, and not Integrated Authentication.)

To use SQL Server, set this to Server=server;Initial Catalog=database;MultipleActiveResultSets=true;Integrated Security=SSPI; for Integrated Authentication
or Server=server;Initial Catalog=database;MultipleActiveResultSets=true;User Id=sqlserveruser;Password=sqlserverpassword; for SQL Server Authentication

To use Access, set this to Provider=Microsoft.Jet.OLEDB.4.0;Data Source=filename